BDBM50396087 CHEMBL2170747

SMILES Oc1ccc2nc(NC(=O)c3c(F)ccc(O)c3F)sc2c1

InChI Key InChIKey=WAIPUKHVRXNDDF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50396087   

TargetCytochrome P450 2B6(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50396087(CHEMBL2170747)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human CYP2B6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50396087(CHEMBL2170747)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50396087(CHEMBL2170747)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50396087(CHEMBL2170747)
Affinity DataIC50:  13nMAssay Description:Inhibition of human placenta 17beta-HSD1 cytosolic fraction using unlabelled and [2,4,6,7-3H]estrone as substrate after 10 mins by HPLC analysis in p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50396087(CHEMBL2170747)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50396087(CHEMBL2170747)
Affinity DataIC50:  37nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells using unlabelled and [2,4,6,7-3H]estrone as substrate preincubated for 30 mins prior to substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50396087(CHEMBL2170747)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of human placenta 17beta-HSD2 microsomal fraction using unlabelled and [2,4,6,7-3H]estradiol as substrate after 20 mins by HPLC analysis i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50396087(CHEMBL2170747)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed