BDBM50396550 CHEMBL2171131

SMILES Nc1ncc(-c2cn[nH]c2)c2scc(-c3ccc4N(CCc4c3)C(=O)Cc3ccccc3)c12

InChI Key InChIKey=NXZHFEXEUNSRPZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396550   

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))TBA

LigandBDBM50396550(CHEMBL2171131)Copy SMILESCopy InChI

Affinity DataIC50: <15nMAssay Description:Inhibition of PERK (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails PubMed
Copy BDB DOI

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))TBA

LigandBDBM50396550(CHEMBL2171131)Copy SMILESCopy InChI

Affinity DataIC50:  0.900nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI