BDBM50396601 CHEMBL2171902
SMILES CN1c2ccc(O)cc2C(=C)c2ccccc2C1=O
InChI Key InChIKey=VGQGXKVPVNOLEN-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50396601
Affinity DataIC50: 1.10E+4nMAssay Description:Transactivational antagonist activity at human LXRbeta transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced lucif...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Antagonist activity at human LXR-alpha transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay in presence of 0.3 uM N-(4-(1,1,1,3...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at human LXRalpha expressed in HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/LXR-beta(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Transrepression activity of LXR in human THP1 cells assessed as inhibition of LPS-induced IL-6 level after 18 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at human LXR-beta transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay in presence of 0.1 uM N-(4-(1,1,1,3,...More data for this Ligand-Target Pair