BDBM50397558 CARPROFEN::CHEMBL2171249

SMILES C[C@H](C(O)=O)c1ccc2c(c1)[nH]c1ccc(Cl)cc21

InChI Key InChIKey=PUXBGTOOZJQSKH-QMMMGPOBSA-N

Data  3 IC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50397558   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Istituto Italiano di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50397558(CARPROFEN | CHEMBL2171249)
Show SMILES C[C@H](C(O)=O)c1ccc2c(c1)[nH]c1ccc(Cl)cc21
Show InChI InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)/t8-/m0/s1
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human COX2 pre-incubated for 10 mins before substrate addition by enzyme immunoassayMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Istituto Italiano di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50397558(CARPROFEN | CHEMBL2171249)
Show SMILES C[C@H](C(O)=O)c1ccc2c(c1)[nH]c1ccc(Cl)cc21
Show InChI InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)/t8-/m0/s1
Affinity DataIC50: 6.42E+4nMAssay Description:Inhibition of FAAH in rat brain homogenates pre-incubated for 10 mins before addition of [3H]anandamide and [3H]AEA substrates for 30 mins by liquid ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Istituto Italiano di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50397558(CARPROFEN | CHEMBL2171249)
Show SMILES C[C@H](C(O)=O)c1ccc2c(c1)[nH]c1ccc(Cl)cc21
Show InChI InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)/t8-/m0/s1
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of ovine COX1 pre-incubated for 10 mins before arachidonic acid substrate addition by enzyme immunoassayMore data for this Ligand-Target Pair