BDBM50397641 CHEMBL2181754
SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)C1CC1
InChI Key InChIKey=MPEHLMJOBXIHAL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50397641
Affinity DataIC50: 13nMAssay Description:Antagonist activity at CRTh2 receptor in human eosinophil assessed as inhibition of PGD2-induced cell shape changeMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding at 1 t...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...More data for this Ligand-Target Pair