BDBM50397965 CHEMBL2180789

SMILES FC(F)(F)Oc1cccc(c1)-n1ccc(=O)c(n1)-c1ccnn1-c1ccccc1

InChI Key InChIKey=NAIXHNHQENAMNS-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397965   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))TBA

LigandBDBM50397965(CHEMBL2180789)Copy SMILESCopy InChI

Affinity DataIC50:  0.0190nMAssay Description:Inhibition of full-length recombinant human PDE10A by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDB

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))TBA

LigandBDBM50397965(CHEMBL2180789)Copy SMILESCopy InChI

Affinity DataIC50:  14nMAssay Description:Inhibition of PDEDA2 using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI