BDBM50398058 CHEMBL2181933::US8722709, 24
SMILES Cc1ccccc1CCc1ccnc(NC(N)=O)c1
InChI Key InChIKey=MOTDSKKJECQMDW-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50398058
Affinity DataIC50: 7.10nMpH: 7.4Assay Description:The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Displacement of TAMRA-labeled Dexamethasone from human mineralocorticoid receptor expressed in baculovirus infected insect cell lysate after 60 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at Gal4-fused human MR LBD expressed in HEK293T cells assessed as inhibition of aldosterone-induced transactivation activity afte...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Displacement of TAMRA-labeled dexamethasone from full-length human mineralocorticoid receptor expressed in baculovirus infected insect cells after 60...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Competitive antagonist activity at human mineralocorticoid receptor expressed in MR-UAS-bla HEK 293T cells assessed as inhibition of aldosterone-indu...More data for this Ligand-Target Pair