BDBM50398062 CHEMBL2181930

SMILES CC1(C)OC(=S)Nc2ccc(NS(=O)(=O)c3cccs3)cc12

InChI Key InChIKey=GHXBKNOADUCFQA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398062   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398062(CHEMBL2181930)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at mineralocorticoid receptor expressed in african green monkey COS7 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(RAT)
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50398062(CHEMBL2181930)
Affinity DataIC50:  21nMAssay Description:Displacement of [3H]-Aldosterone from MR in rat kidney cytosolic fraction measured after 18 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(RAT)
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50398062(CHEMBL2181930)
Affinity DataIC50:  21nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor after 18 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed