BDBM50399710 CHEMBL2178953
SMILES Cc1nc(C)c(nc1C(N)=O)-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1
InChI Key InChIKey=YXFNPRHZMOGREC-SHTZXODSSA-N
Data 22 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50399710
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant FLAG-tagged human DGAT1 expressed in SF9 cells after 1 hr by TopCount assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of DGAT1 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of DGAT1 in rat adipose tissue assessed as reduction in triacylglycerol synthesisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human ACAT1 by liquid scintillographyMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of PDE10A1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.05E+4nMAssay Description:Inhibition of muscarinic M2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of DGAT1 in dog liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of DGAT1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of DGAT1 in rat liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ACAT2 by liquid scintillographyMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human DGAT2 by liquid scintillographyMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of DGAT1 in human adipose tissue assessed as reduction in triacylglycerol synthesisMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant FLAG-tagged human DGAT2 expressed in SF9 cells after 1 hr by TopCount assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of DGAT1 in human HuTu80 cellsMore data for this Ligand-Target Pair