BDBM50400037 CHEMBL2177733::US9169259, I-5

SMILES CC1CCCN1c1cccc(Nc2cc(nn3ccnc23)-c2ccccc2)n1

InChI Key InChIKey=OLNOLIZABHZSEW-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50400037   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50400037(CHEMBL2177733 | US9169259, I-5)
Affinity DataIC50:  127nMAssay Description:Inhibition of human recombinant spleen tyrosine kinase (360 to 635 amino acid residues) after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50400037(CHEMBL2177733 | US9169259, I-5)
Affinity DataIC50:  127nMAssay Description:Assay plates: 96-well MultiScreen 0.65 um filter plates (Millipore Cat. No.: MADVNOB10)Streptavidin coated beads: Streptavidin Sepharose, suspension ...More data for this Ligand-Target Pair