BDBM50400047 BIIB-057::CHEMBL2177736::US9579320, Example 87

SMILES N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc(c2)-n2nccn2)n1

InChI Key InChIKey=TXGKRVFSSHPBAJ-JKSUJKDBSA-N

Data  36 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400047   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Jilin University

LigandPNGBDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
Affinity DataIC50:  10.5nMpH: 7.5 T: 2°CAssay Description:Briefly, 10 μL per well reactions contained ATP concentration at 25 μm for Syk,2 μm Tyr2 peptide substrate in 50 mm HEPES (PH 7.5), 0....More data for this Ligand-Target Pair