BDBM50400147 CHEMBL2179014

SMILES O=C(N[C@H]1C2CC3CC1C[C@](O)(C3)C2)c1cnc(N[C@H]2CCOC2)nc1C1CCCC1

InChI Key InChIKey=VMTZDIHMLVWUQZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50400147   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400147BDBM50400147(CHEMBL2179014)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human 11beta-HSD1 by HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400147BDBM50400147(CHEMBL2179014)
Affinity DataIC50: 21nMAssay Description:Inhibition of human 11beta-HSD1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400147BDBM50400147(CHEMBL2179014)
Affinity DataIC50: 32nMAssay Description:Inhibition of mouse 11beta-HSD1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400147BDBM50400147(CHEMBL2179014)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400147BDBM50400147(CHEMBL2179014)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 17beta-HSD1 by HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed