BDBM50400315 CHEMBL2181312

SMILES Fc1cc2COCC=CCOCc3cc(Nc4nccc(n4)-c(c1)c2)ccc3OCCN1CCCC1

InChI Key InChIKey=KJOZOAQMGSIFNM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50400315   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400315(CHEMBL2181312)
Affinity DataIC50:  380nMAssay Description:Inhibition of recombinant JAK1 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400315(CHEMBL2181312)
Affinity DataIC50:  36nMAssay Description:Inhibition of recombinant TYK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400315(CHEMBL2181312)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400315(CHEMBL2181312)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed