BDBM50400316 CHEMBL2181087

SMILES COc1cc2Nc3nccc(n3)-c3cccc(COCC=CCOCc(c2)c1OCCN1CCCC1)c3

InChI Key InChIKey=KYEFPHMQFQFRLZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50400316   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400316(CHEMBL2181087)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant JAK1 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400316(CHEMBL2181087)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant TYK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400316(CHEMBL2181087)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400316(CHEMBL2181087)
Affinity DataIC50:  36nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed