BDBM50400318 CHEMBL2181085

SMILES Nc1cc2COCC=CCOCc3cccc(c3)-c3ccnc(Nc(c1)c2)n3

InChI Key InChIKey=LVRXBZNKAGNVHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50400318   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400318(CHEMBL2181085)
Affinity DataIC50:  52nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400318(CHEMBL2181085)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed