BDBM504004 US11034692, Compound 268::trans-N-[8-amino-6-(5-hydroxy-2- methylphenyl)-2,7-naphthyridin-3-yl]-2- (1-methyl-1H-pyrazol-4-yl)cyclopropane- 1-carboxamide
SMILES Cc1ccc(O)cc1-c1cc2cc(NC(=O)C3CC3c3cnn(C)c3)ncc2c(N)n1
InChI Key InChIKey=HPJXSTKOZQAULW-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 504004
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 0.147nMAssay Description:Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...More data for this Ligand-Target Pair