BDBM50400783 CHEMBL1608462

SMILES CC(C)n1ncc2c(cc(nc12)C1CC1)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key InChIKey=HNHUNRACMOTTER-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50400783   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50400783(CHEMBL1608462)
Affinity DataKi:  700nMAssay Description:Non-competitive inhibition of human EZH2 using [3H]-SAM as substrate in presence of H3K27AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50400783(CHEMBL1608462)
Affinity DataKi:  700nMAssay Description:Competitive inhibition of human EZH2 using H3K27A as substrate in presence of SAMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed