BDBM50401268 CHEMBL2206914::US8772480, 365

SMILES Cc1nc(N)nc(n1)-c1cccnc1Nc1cnc(Cl)c(NS(=O)(=O)C2CC2)c1

InChI Key InChIKey=FOVDAQSOCPEZCB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401268   

LigandPNGBDBM50401268(CHEMBL2206914 | US8772480, 365)
Affinity DataKi:  6nMAssay Description:The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kalpha, PI3Kbeta, PI...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM50401268(CHEMBL2206914 | US8772480, 365)
Affinity DataKi:  11nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110alpha expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM50401268(CHEMBL2206914 | US8772480, 365)
Affinity DataIC50:  345nMAssay Description:The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...More data for this Ligand-Target Pair
In DepthDetails US Patent