BDBM50401339 CHEMBL4161447

SMILES Cl.Cl.CC(=N)NCc1cccc(CNC(=O)[C@@H]2CCCN2)c1

InChI Key InChIKey=VFWZUEHZTBFYTG-UTLKBRERSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401339   

TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50401339(CHEMBL4161447)
Affinity DataIC50:  58nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of Chieti "G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50401339(CHEMBL4161447)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant rat nNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of Chieti "G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50401339(CHEMBL4161447)
Affinity DataIC50:  2.65E+5nMAssay Description:Inhibition of recombinant bovine eNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed