BDBM50401900 CHEMBL2207198

SMILES O=C(NCCCNc1nc(Nc2ccc(cc2)N2CCOCC2)ncc1C1CC1)C1CCC1

InChI Key InChIKey=CJPMSUUANYLPET-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50401900   

TargetAurora kinase B(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401900(CHEMBL2207198)
Affinity DataIC50:  700nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401900(CHEMBL2207198)
Affinity DataIC50:  30nMAssay Description:Inhibition of IKKepsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401900(CHEMBL2207198)
Affinity DataIC50:  630nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401900(CHEMBL2207198)
Affinity DataIC50:  6nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP/microtubule affinity-regulating kinase 3(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401900(CHEMBL2207198)
Affinity DataIC50:  12nMAssay Description:Inhibition of MARK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401900(CHEMBL2207198)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of MNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Mus musculus)
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401900(CHEMBL2207198)
Affinity DataIC50:  58nMAssay Description:Inhibition of TBK1-mediated RANTES release in LPS-stimulated mouse RAW264.7 cells compound incubated for 30 mins prior LPS challenge measured after 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase BRSK2(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401900(CHEMBL2207198)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of BRSK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed