BDBM50402265 CHEMBL2164280::US8802861, 1

SMILES CC(=O)Nc1nc(C)c(s1)-c1csc(Nc2cccc(c2)C(O)=O)n1

InChI Key InChIKey=AYSRHUJFCKXTHN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50402265   

LigandPNGBDBM50402265(CHEMBL2164280 | US8802861, 1)
Affinity DataIC50:  10nMAssay Description:The efficacy of compounds of the invention in inhibiting the PI3K induced-lipid phosphorylation may be tested in the following binding assay.The assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TAO2(Rattus norvegicus)
University Of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50402265(CHEMBL2164280 | US8802861, 1)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50402265(CHEMBL2164280 | US8802861, 1)
Affinity DataIC50:  5nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed