BDBM50403099 CHEMBL2216892

SMILES C[C@H](Nc1ncnc(N)c1C#N)c1nc2ccc(F)cc2c(NCCS(C)(=O)=O)c1-c1ccccc1

InChI Key InChIKey=UTIUYGXIWRQSMG-HNNXBMFYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50403099   

LigandPNGBDBM50403099(CHEMBL2216892)
Affinity DataKi:  2.30nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403099(CHEMBL2216892)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) assessed as inhibition of AKT phosphorylation by cell-based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403099(CHEMBL2216892)
Affinity DataIC50:  19nMAssay Description:Inhibition of PI3Kgamma (unknown origin) by biochemical Alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403099(CHEMBL2216892)
Affinity DataIC50:  500nMAssay Description:Inhibition of PI3Kbeta (unknown origin) by biochemical Alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403099(CHEMBL2216892)
Affinity DataIC50:  900nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by biochemical Alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403099(CHEMBL2216892)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of PI3Kdelta (unknown origin) by biochemical Alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed