BDBM504034 (1R,2R)N-(8-amino-6-(2-chloro-6-fluorophenyl)-2,7-naphthyridin-3-yl)-2-(1-methyl-1H-pyrazol-4-yl)cyclopropanecarboxamide (Compound 302) and (1S,2S)N-(8-amino-6-(2-chloro-6-fluorophenyl)-2,7-naphthyridin-3-yl)-2-(1-methyl-H-pyrazol-4-yl)cyclopropanecarboxamide ::US11034692, Compound 303
SMILES Cn1cc(cn1)[C@H]1C[C@@H]1C(=O)Nc1cc2cc(nc(N)c2cn1)-c1c(F)cccc1Cl
InChI Key InChIKey=FQPLGQZROUJXDM-KGLIPLIRSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 504034
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 0.0270nMAssay Description:Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...More data for this Ligand-Target Pair