BDBM50403672 CHEMBL24665
SMILES NCCc1cnc([nH]1)-c1cccc(c1)C(F)(F)F
InChI Key InChIKey=NFUYVKMAGIJYKB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50403672
Affinity DataKi: 1.26E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Freie Universit£T Berlin
Curated by ChEMBL
Freie Universit£T Berlin
Curated by ChEMBL
Affinity DataEC50: 1.28E+3nMAssay Description:H1-Histamine receptor agonism on Guinea pig aorta was evaluated (SEM 0.03-0.18)More data for this Ligand-Target Pair
Affinity DataEC50: 1.59E+3nMAssay Description:Agonist activity at human recombinant histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2 by steady-state GTPase ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against human Histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 251nMAssay Description:Agonist activity at human recombinant histamine H1 receptor expressed in Sf9 cells coexpressing RGS4 by steady-state GTPase activity assayMore data for this Ligand-Target Pair