BDBM50411023 CHEMBL208779
SMILES CCC1(CC(O)(C(=O)Nc2ccc3c(c2)c(C)noc3=O)C(F)(F)F)CCCc2c(cccc12)[N+]([O-])=O
InChI Key InChIKey=QPIVWEONKJJPRQ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50411023
Affinity DataIC50: 251nMAssay Description:Activity at GR assessed as ability to antagonize dexamethasone-induced MMTV luciferase reporter gene transactivation in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair