BDBM50411043 CHEMBL212059
SMILES Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3(CCCc4ccccc34)c3ccccc3)C(F)(F)F)cc12
InChI Key InChIKey=KFYBVRFVPSMIAT-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50411043
Affinity DataIC50: 14nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+3nMAssay Description:Activity at GR assessed as ability to antagonize dexamethasone-induced MMTV luciferase reporter gene transactivation in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair