BDBM50411045 CHEMBL208840
SMILES CCC1(CC(O)(C(=O)Nc2ccc3c(c2)c(C)noc3=O)C(F)(F)F)CCCCc2ccccc12
InChI Key InChIKey=NVONLYUUKCINFL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50411045
Affinity DataIC50: 7.90nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+4nMAssay Description:Agonist activity at GR assessed as MMTV-mediated transactivation of renilla luciferase gene in human A549 cells relative to DexamethasoneChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair