BDBM50411051 CHEMBL379158

SMILES Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3CCCc4c(cccc34)C#N)C(F)(F)F)cc12

InChI Key InChIKey=ASBUXVKPNDZGBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50411051   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411051(CHEMBL379158)
Affinity DataIC50:  16nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411051(CHEMBL379158)
Affinity DataIC50: <1.00E+3nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed