BDBM50412707 CHEMBL230333

SMILES CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CO)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(O)=O

InChI Key InChIKey=ZRCUKBVXFDZBKP-XJEBPGRNSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50412707   

TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50412707(CHEMBL230333)
Affinity DataEC50:  0.676nMAssay Description:Agonist activity at human NPSR Ile107 expressed in HEK293 cells assessed as induction of calcium mobilization after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50412707(CHEMBL230333)
Affinity DataEC50:  0.851nMAssay Description:Agonist activity at human NPSR Asn107 expressed in HEK293 cells assessed as induction of calcium mobilization after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Mus musculus)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50412707(CHEMBL230333)
Affinity DataEC50:  12nMAssay Description:Agonist activity at mouse NPSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Mus musculus)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50412707(CHEMBL230333)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at mouse NPSR expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Mus musculus)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50412707(CHEMBL230333)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at mouse recombinant NPS receptor expressed in HEK293 cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Mus musculus)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50412707(CHEMBL230333)
Affinity DataEC50:  2.24nMAssay Description:Agonist activity at mouse NPSR expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed