BDBM50412798 EMICERFONT
SMILES COc1ccc(N2CCc3c2nc(C)cc3-n2ccc(n2)N2CCNC2=O)c(C)c1
InChI Key InChIKey=JFHJGXQFESYQGY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50412798
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: 72.4nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO cells assessed as effect on sauvagine-induced cAMP productionMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 66.1nMAssay Description:Displacement of [125I]sauvagine from human recombinant CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair