BDBM50413498 CHEMBL475621::UR-PI294

SMILES CCC(=O)NC(N)=NCCCc1cnc[nH]1

InChI Key InChIKey=NDEWHFAPFGGMKU-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50413498   

TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50413498(CHEMBL475621 | UR-PI294)
Affinity DataEC50:  302nMAssay Description:Agonist activity at histamine H2 receptor in guinea pig atrium assessed as increase in heart rateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50413498(CHEMBL475621 | UR-PI294)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human H3 receptor expressed in insect Sf9 cells co-expressing Gialpha2, Gbeta1gamma2 and RGS4 assessed as gamma[32P]GTP binding b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50413498(CHEMBL475621 | UR-PI294)
Affinity DataEC50:  3.47E+3nMAssay Description:Agonist activity at human H1 receptor expressed in insect Sf9 cells co-expressing RGS4 assessed as gamma[32P]GTP binding by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50413498(CHEMBL475621 | UR-PI294)
Affinity DataEC50:  3.31E+3nMAssay Description:Agonist activity at rat H4R by [35S]-GTPgammaS-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50413498(CHEMBL475621 | UR-PI294)
Affinity DataEC50:  372nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50413498(CHEMBL475621 | UR-PI294)
Affinity DataEC50:  794nMAssay Description:Agonist activity at mouse H4R by [35S]-GTPgammaS-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50413498(CHEMBL475621 | UR-PI294)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human H4R by [35S]-GTPgammaS-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50413498(CHEMBL475621 | UR-PI294)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human H4 receptor expressed in insect Sf9 cells co-expressing RGS19 fusion protein and Gialpha2, Gbeta1gamma2 assessed as gamma[3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed