BDBM50414921 CHEMBL570812
SMILES COc1nn(-c2ccc(NC(=O)OCc3ccccc3)c(C)c2)c(=O)o1
InChI Key InChIKey=QTENHWTVRQKWRI-UHFFFAOYSA-N
Data 30 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 30 hits for monomerid = 50414921
Affinity DataIC50: 144nMAssay Description:Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of MAGL (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Irreversible inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Irreversible inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate preincubated for 60 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human MAGL using 4-Nitrophenylacetate substrate incubated for 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 0 min followed by substrate addition by ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 30 mins followed by substrate addition b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 60 mins followed by substrate addition b...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of M£Nster
Curated by ChEMBL
University Of M£Nster
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of FAAH in Sprague-Dawley rat brain microsomes assessed as N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide conversion to 4-pyren-1-ylbutanoic ac...More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of human recombinant MAGL-mediated 1,3-dihydroxypropan-1-yl 4-pyren-1-ylbutanoate conversion to 4-pyren-1-ylbutanoic acid preincubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of FAAH (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of MAGL (unknown origin) using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Inhibition of MAGL (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 20.4nMAssay Description:Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 77.6nMAssay Description:Inhibition of human recombinant FAAH-maltose binding proteinMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of recombinant human MAGL using 1,3-dihydroxypropan-2-yl 4-pyren-1-yl-butanoate as substrate after 45 mins by fluorescence-based reversed ...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 30 mins by colorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant human MAGLMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of M£Nster
Curated by ChEMBL
University Of M£Nster
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human C-terminal His-tagged MAGL expressed in Escherichia coli using 4-NPA as substrate measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 134nMAssay Description:Inhibition of human recombinant MAGL using 4-NPA as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant MAGLMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of M£Nster
Curated by ChEMBL
University Of M£Nster
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of MAGL (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 424nMAssay Description:Inhibition of human MAGL using 4-Nitrophenylacetate as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of human recombinant MAGL using 1,3-dihydroxypropan-2-yl 4-pyren-1-ylbutanoate as substrate measured after 45 mins by reverse-phase HPLC-b...More data for this Ligand-Target Pair
Affinity DataIC50: 134nMAssay Description:Inhibition of human recombinant MAGL using 4-NPA substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate incubated for 30 mins by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 146nMAssay Description:Irreversible inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair