BDBM50418259 CHEMBL1765756

SMILES Cc1cc(nc(N)n1)-c1ccc2c(N)n[nH]c2c1

InChI Key InChIKey=JZOJBOMGNJTZMY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50418259   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418259(CHEMBL1765756)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418259(CHEMBL1765756)
Affinity DataIC50:  126nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418259(CHEMBL1765756)
Affinity DataIC50:  7.94E+3nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418259(CHEMBL1765756)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418259(CHEMBL1765756)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed