BDBM50419762 CHEMBL1949920

SMILES CN(C(=O)c1cc2CCOc3cc(ccc3-c2s1)-c1cc[nH]n1)c1ccccc1Cl

InChI Key InChIKey=VYNINSZPZUFHMR-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50419762   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50419762(CHEMBL1949920)Copy SMILESCopy InChI

Affinity DataKi:  3nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50419762(CHEMBL1949920)Copy SMILESCopy InChI

Affinity DataKi:  247nMAssay Description:Apparent binding affinity to PI3Kbeta using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI