BDBM50419771 CHEMBL1950036
SMILES CN(C(=O)c1cc2CCOc3ccc(cc3-c2s1)C#N)c1ccccc1Cl
InChI Key InChIKey=APBMXQOKSKYMHJ-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50419771
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 144nMAssay Description:Apparent binding affinity to PI3Kbeta using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair