BDBM50419860 CHEMBL1957471
SMILES COc1cccc(-c2cccc(c2)[C@@]2(N=C(N)N3CC(F)(F)CN=C23)c2ccncc2)c1F
InChI Key InChIKey=RECVUKARQVUVBY-DEOSSOPVSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50419860
Affinity DataIC50: 54nMAssay Description:Inhibition of BACE-1-mediated sAPPbeta production in human SH-SY5Y cells after 16 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human BACE-1 using (Eu)CEVNLDAEFK(Qsy7) as substrate preincubated for 10 mins prior substrate addition measured after 15 mins by FRET-b...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human BACE-1 using (Eu)CEVNLDAEFK(Qsy7) as substrate preincubated for 10 mins prior substrate addition measured after 15 mins by FRET-b...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of BACE-1-mediated sAPPbeta production in human SH-SY5Y cells after 16 hrsMore data for this Ligand-Target Pair