BDBM50420459 CHEMBL2086528

SMILES C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)C34CC5CC(CC(C5)C3)C4)CC2)cc1

InChI Key InChIKey=NWFPBQYIKXKLNF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50420459   

TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Evotec (Uk)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420459BDBM50420459(CHEMBL2086528)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Evotec (Uk)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420459BDBM50420459(CHEMBL2086528)
Affinity DataIC50: 10nMAssay Description:Inhibition of TG2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420459BDBM50420459(CHEMBL2086528)
Affinity DataIC50: 16nMAssay Description:Inhibition of mouse recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain(Human)
Evotec (Uk)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420459BDBM50420459(CHEMBL2086528)
Affinity DataIC50: 180nMAssay Description:Inhibition of thrombin activated human F13a by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Evotec (Uk)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420459BDBM50420459(CHEMBL2086528)
Affinity DataIC50: 770nMAssay Description:Inhibition of human TG2 in HEK cells by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 6(Human)
Evotec (Uk)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420459BDBM50420459(CHEMBL2086528)
Affinity DataIC50: 840nMAssay Description:Inhibition of human recombinant TG6 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase K(Human)
Evotec (Uk)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420459BDBM50420459(CHEMBL2086528)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant TG1 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase E(Human)
Evotec (Uk)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420459BDBM50420459(CHEMBL2086528)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of thrombin activated human TG3 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed