BDBM50421184 CHEMBL2086798

SMILES COc1c(sc2c1c(=O)n(CC(=O)c1ccccc1)c1ccccc21)C(=O)NCCN1CCCC1

InChI Key InChIKey=QJZWMYPQWAPKKV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50421184   

TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421184(CHEMBL2086798)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed