BDBM50424532 CHEMBL2312154

SMILES COc1ccc(cc1-c1ccnc(Nc2ccc(N3CCC(CC3)N(C)C)c(F)c2)c1)C#N

InChI Key InChIKey=KXMSGPHFWCUEMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424532   

TargetTRAF2 and NCK-interacting protein kinase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424532(CHEMBL2312154)
Affinity DataIC50:  11nMAssay Description:Inhibition of TNIK (unknown origin) by ADP glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424532(CHEMBL2312154)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of TNIK-mediated TCF4/beta-catenin transcription in human HCT116 cells by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed