BDBM50424957 CHEMBL2316158::US9409845, Table 1, Compound 19: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(4-methylsulphonylbenzylidene)cyclohexanone
SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(cc3)S(C)(=O)=O)C2=O)c1
InChI Key InChIKey=KCKFFUAUNCDZHZ-GDAWTGGTSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50424957
Affinity DataIC50: 1.96E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair