BDBM50425385 CHEMBL2311807

SMILES Cc1cn(cn1)-c1cc(F)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1

InChI Key InChIKey=SDYGMEWQBSWSIW-UHFFFAOYSA-N

Data  8 IC50  6 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50425385   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataKd:  3.5nMAssay Description:Binding affinity to human c-KitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataKd:  9.40nMAssay Description:Binding affinity to human ABL1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  26nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of human LCK using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataKd:  14nMAssay Description:Binding affinity to human DDR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  179nMAssay Description:Inhibition of human DDR2 using KKSRGDYMTMQIG peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  10nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  750nMAssay Description:Inhibition of human ABL1 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataKd:  8.5nMAssay Description:Binding affinity to human PDGFRbeataMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataKd:  24nMAssay Description:Binding affinity to human PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataKd:  58nMAssay Description:Binding affinity to human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  118nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed