BDBM50425963 CHEMBL2314369

SMILES O=[#6]-1\[#6](=[#6](\C#N)C#N)-c2cccc3cccc-1c23

InChI Key InChIKey=WYZUQHDRPNJOCG-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50425963   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50425963(CHEMBL2314369)
Affinity DataKi:  2.85E+3nMAssay Description:Inhibition of FAM-Bid peptide binding to Mcl1 (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization-based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Universit£

Curated by ChEMBL
LigandPNGBDBM50425963(CHEMBL2314369)
Affinity DataKi: >2.94E+5nMAssay Description:Inhibition of Escherichia coli thymidylate synthase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50425963(CHEMBL2314369)
Affinity DataKi: >3.09E+5nMAssay Description:Inhibition of human thymidylate synthase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50425963(CHEMBL2314369)
Affinity DataKd:  5.23E+4nMAssay Description:Binding affinity to his-tagged Mcl-1 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50425963(CHEMBL2314369)
Affinity DataIC50:  7.15E+4nMAssay Description:Inhibition of FAM-Bid peptide binding to Mcl1 (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization-based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed