BDBM50426807 CHEMBL2322779

SMILES NC(=O)c1cnc2-c3sc(cc3CCOc2c1)-c1[nH]nnc1-c1ccc(F)cc1F

InChI Key InChIKey=DCRLRAYKNYJGRE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50426807   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50426807(CHEMBL2322779)Copy SMILESCopy InChI

Affinity DataIC50:  500nMAssay Description:Inhibition of PI3Kalpha-mediated AKT Ser 473 phosphorylation in human PC3 cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI