BDBM50426810 CHEMBL2322501

SMILES CC(=O)Nc1nc(c([nH]1)-c1cc2CCOc3cccnc3-c2s1)-c1ccccc1Cl

InChI Key InChIKey=RQIONNMMALFGKD-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50426810   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50426810(CHEMBL2322501)Copy SMILESCopy InChI

Affinity DataIC50:  36nMAssay Description:Inhibition of PI3Kalpha-mediated AKT Ser 473 phosphorylation in human PC3 cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI