BDBM50427053 CHEMBL2322541

SMILES NCc1ccc(CNC(=O)Cc2ccc(cc2)-c2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=SOKKPDFWPPGKPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50427053   

TargetBeta-secretase 2(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427053(CHEMBL2322541)
Affinity DataIC50:  3.19E+5nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427053(CHEMBL2322541)
Affinity DataIC50:  5.89E+4nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed