BDBM50427189 CHEMBL2324167

SMILES CCCS(=O)(=O)N1CCN(CC1)C1(CNC(=O)c2ccc(Cl)cc2Cl)CCCCC1

InChI Key InChIKey=UOVNJWABMVOCSX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50427189   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50427189(CHEMBL2324167)
Affinity DataIC50:  23nMAssay Description:Inhibition of GlyT1a in human JAR cells assessed as inhibition of [3H]glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50427189(CHEMBL2324167)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibition of human glycine transporter-2 expressed in HEK293 cells assessed as reduction in [14C]glycine uptake preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50427189(CHEMBL2324167)
Affinity DataIC50:  23nMAssay Description:Inhibition of glycine transporter-1B in human JAR cells assessed as reduction in [14C]glycine uptake preincubated for 10 mins followed by [14C]glycin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50427189(CHEMBL2324167)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibition of human GlyT2 expressed in HEK293 cells assessed as inhibition of [3H]glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed