BDBM50428344 CHEMBL2331711

SMILES NC1=N[C@]2(C[C@H]2CCS1)c1cc(NC(=O)c2ccc(Cl)cn2)ccc1Cl

InChI Key InChIKey=SEFSAJZVMRSUIZ-MGNBDDOMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50428344   

TargetBeta-secretase 2(Rattus norvegicus)
Temple University

Curated by ChEMBL
LigandPNGBDBM50428344(CHEMBL2331711)
Affinity DataIC50:  690nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed