BDBM50429046 CHEMBL2334882::US9359372, DC037081
SMILES COc1c(O)ccc2C[C@@H]3N(CCc4cc5CCOc5cc34)Cc12
InChI Key InChIKey=HYIGJQLIWSXNQW-KRWDZBQOSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50429046
Affinity DataKi: 7.5nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor (unknown origin) expressed in human HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 17.3nM ΔG°: -10.8kcal/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Affinity DataKi: 147nM ΔG°: -9.47kcal/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 480nMAssay Description:Displacement of [3H]Ketanserin from 5-HT2A receptor (unknown origin) expressed in HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor (unknown origin) expressed in HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair