BDBM50429052 CHEMBL2334881::US9359372, DC037082

SMILES COc1c(O)ccc2C[C@@H]3N(CCc4cc5OCCOc5cc34)Cc12

InChI Key InChIKey=XTOFAUDOQPKYRI-INIZCTEOSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50429052   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50429052(CHEMBL2334881 | US9359372, DC037082)
Affinity DataKi:  7.51nM ΔG°:  -11.3kcal/mole IC50:  14.7nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50429052(CHEMBL2334881 | US9359372, DC037082)
Affinity DataKi:  208nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor (unknown origin) expressed in HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50429052(CHEMBL2334881 | US9359372, DC037082)
Affinity DataKi:  363nMAssay Description:Displacement of [3H]Ketanserin from 5-HT2A receptor (unknown origin) expressed in HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed