BDBM50429775 CHEMBL2336353::N-(2-Hydroxyphenyl)Cinnamamide

SMILES Oc1ccccc1NC(=O)\C=C\c1ccccc1

InChI Key InChIKey=CYJJBQPBDGQQFZ-ZHACJKMWSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50429775   

TargetShiga toxin subunit A(Shigella dysenteriae)
TBA

Curated by ChEMBL
LigandPNGBDBM50429775(CHEMBL2336353 | N-(2-Hydroxyphenyl)Cinnamamide)
Affinity DataKi:  1.87E+4nMAssay Description:Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit assessed as change in transition temperature by SYPRO orange dye based fluorescence-b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50429775(CHEMBL2336353 | N-(2-Hydroxyphenyl)Cinnamamide)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of human recombinant MMP1 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50429775(CHEMBL2336353 | N-(2-Hydroxyphenyl)Cinnamamide)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human recombinant MMP2 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50429775(CHEMBL2336353 | N-(2-Hydroxyphenyl)Cinnamamide)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of human recombinant MMP9 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed